Try this homemade San Antonio Casserole recipe the whole family will love. Made with lean ground round, onion, oil and cream of mushroom soup. Easy step…
This San Antonio Casserole relies on simple, everyday ingredients such as lean ground round, medium onion, finely chopped, oil and milk. It comes together quickly and makes 4 servings, at about 639 kcal each. The step-by-step instructions below are written to be easy to follow, even on a busy day.
It works as a light main on its own or as a starter alongside crusty bread, and it's just as good for a cozy night in as it is for feeding a crowd. Leftovers keep well, so it's a smart choice for meal prep too.
Updated Jun 30, 2026