Try this homemade Mexican Casserole recipe the whole family will love. Made with ground beef, cream of mushroom soup, cream of chicken and Ro-Tel tomato…
This Mexican Casserole relies on simple, everyday ingredients such as ground beef, cream of mushroom soup, velveeta cheese and picante sauce to taste. It comes together quickly and makes 4 servings, at about 949 kcal each. The step-by-step instructions below are written to be easy to follow, even on a busy day.
It works as a light main on its own or as a starter alongside crusty bread, and it's just as good for a cozy night in as it is for feeding a crowd. Leftovers keep well, so it's a smart choice for meal prep too.
Updated Jun 30, 2026