How many servings does this recipe make?

This recipe makes 4 servings. You can adjust the portion size directly on this page.

What ingredients do I need for Spinach-Chicken Pasta Casserole(Heart Healthy) ?

You need 12 ingredients. The key ingredients include: 10 oz. uncooked mostaccioli, 10 oz. pkg. frozen spinach, Pam vegetable cooking spray, 2/3 c. chopped onion, and more.

Is Spinach-Chicken Pasta Casserole(Heart Healthy) suitable as pasta & noodles?

Yes, Spinach-Chicken Pasta Casserole(Heart Healthy) falls under the Pasta & Noodles category and is a great choice for this type of meal.

How do I store leftover Spinach-Chicken Pasta Casserole(Heart Healthy) ?

Store leftovers in an airtight container in the refrigerator for up to 3–4 days. Reheat gently before serving.

Spinach-Chicken Pasta Casserole(Heart Healthy)

Name: Spinach-Chicken Pasta Casserole(Heart Healthy)
Prep time: 15 min
Cook time: 30 min
Total time: 45 min
Yield: 4 servings
Ingredients: 10 oz. uncooked mostaccioli; 10 oz. pkg. frozen spinach; Pam vegetable cooking spray; 2/3 c. chopped onion; 2 large cloves garlic, chopped; 1 lb. skinless, boneless chicken, cubed; 2 (14 1/2 oz.) cans tomatoes, undrained; 3 Tbsp. tomato paste; 1 1/4 tsp. dried basil; 3/4 tsp. dried oregano; 1/4 tsp. red hot sauce or 1/4 tsp. crushed red pepper; 1/2 c. grated Parmesan cheese, divided

Try this homemade Spinach-Chicken Pasta Casserole(Heart Healthy) recipe the whole family will love. Made with mostaccioli, frozen spinach, onion and gar…

This Spinach-Chicken Pasta Casserole(Heart Healthy) relies on simple, everyday ingredients such as uncooked mostaccioli, pkg. frozen spinach, pam vegetable cooking spray and chopped onion. It comes together quickly and makes 4 servings, at about 437 kcal each. The step-by-step instructions below are written to be easy to follow, even on a busy day.

It's versatile enough for an easy weeknight dinner yet satisfying enough for guests at the weekend. Serve it with your favorite sides, and keep any leftovers for a quick meal the next day.

Updated Jun 30, 2026

Serves 4 Pasta & Noodles

Tips for the best results

Read through all the steps once before you start and measure out your ingredients first — it makes everything go more smoothly.
Taste as you go and adjust the seasoning before serving.
Avoid overcrowding the pan — cook in batches if needed for the best texture.
Let the dish rest for a few minutes before serving so the flavors settle.
Store leftovers in an airtight container in the fridge and enjoy within a few days.

Variations & substitutions

Feel free to swap in similar ingredients you already have on hand and adjust seasoning to taste.

No specific allergen information. Please check the ingredient list for possible allergens.

My Personal Notes

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Spinach-Chicken Pasta Casserole(Heart Healthy)

Tips for the best results

Variations & substitutions

My Personal Notes

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Frequently Asked Questions