How many servings does this recipe make?

This recipe makes 4 servings. You can adjust the portion size directly on this page.

What ingredients do I need for Pesto-Chicken Penne Casseroles?

You need 11 ingredients. The key ingredients include: 1 package (16 ounces) penne pasta, 6 cups cubed cooked chicken, 4 cups shredded Italian cheese blend, 3 cups fresh baby spinach, and more.

Is Pesto-Chicken Penne Casseroles suitable as pasta & noodles?

Yes, Pesto-Chicken Penne Casseroles falls under the Pasta & Noodles category and is a great choice for this type of meal.

How do I store leftover Pesto-Chicken Penne Casseroles?

Store leftovers in an airtight container in the refrigerator for up to 3–4 days. Reheat gently before serving.

Pesto-Chicken Penne Casseroles Recipe

Name: Pesto-Chicken Penne Casseroles
Prep time: 15 min
Cook time: 30 min
Total time: 45 min
Yield: 4 servings
Ingredients: 1 package (16 ounces) penne pasta; 6 cups cubed cooked chicken; 4 cups shredded Italian cheese blend; 3 cups fresh baby spinach; 1 can (15 ounces) crushed tomatoes; 1 jar (15 ounces) Alfredo sauce; 1-1/2 cups 2% milk; 1 jar (8.1 ounces) prepared pesto; 1/2 cup seasoned bread crumbs; 1/2 cup grated Parmesan cheese; 1 tablespoon olive oil

Try this homemade Pesto-Chicken Penne Casseroles recipe the whole family will love. Made with penne pasta, chicken, Italian cheese and fresh baby spinac…

This Pesto-Chicken Penne Casseroles relies on simple, everyday ingredients such as (16 ounces) penne pasta, cubed cooked chicken, fresh baby spinach and (15 ounces) crushed tomatoes. It comes together quickly and makes 4 servings, at about 1359 kcal each. The step-by-step instructions below are written to be easy to follow, even on a busy day.

It's versatile enough for an easy weeknight dinner yet satisfying enough for guests at the weekend. Serve it with your favorite sides, and keep any leftovers for a quick meal the next day.

Updated Jun 30, 2026

Serves 4 Pasta & Noodles

1359

kcal

Calories

Tips for the best results

Read through all the steps once before you start and measure out your ingredients first — it makes everything go more smoothly.
Taste as you go and adjust the seasoning before serving.
Avoid overcrowding the pan — cook in batches if needed for the best texture.
Let the dish rest for a few minutes before serving so the flavors settle.
Store leftovers in an airtight container in the fridge and enjoy within a few days.

Variations & substitutions

Feel free to swap in similar ingredients you already have on hand and adjust seasoning to taste.

No specific allergen information. Please check the ingredient list for possible allergens.

My Personal Notes

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Pesto-Chicken Penne Casseroles

Tips for the best results

Variations & substitutions

My Personal Notes

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