How many servings does this recipe make?

This recipe makes 4 servings. You can adjust the portion size directly on this page.

What ingredients do I need for Zucchini-Seafood Casserole?

You need 10 ingredients. The key ingredients include: 4 c. (1/4-inch) zucchini slices (3 to 5 medium), 1 1/2 c. Bisquick, 1 1/2 c. shredded sharp American cheese, 1 c. chopped onion, and more.

Is Zucchini-Seafood Casserole suitable as seafood?

Yes, Zucchini-Seafood Casserole falls under the Seafood category and is a great choice for this type of meal.

How do I store leftover Zucchini-Seafood Casserole?

Store leftovers in an airtight container in the refrigerator for up to 3–4 days. Reheat gently before serving.

Zucchini-Seafood Casserole Recipe

Name: Zucchini-Seafood Casserole
Prep time: 15 min
Cook time: 30 min
Total time: 45 min
Yield: 4 servings
Ingredients: 4 c. (1/4-inch) zucchini slices (3 to 5 medium); 1 1/2 c. Bisquick; 1 1/2 c. shredded sharp American cheese; 1 c. chopped onion; 1 (6 1/2 oz.) can crab meat, drained and cartilage removed or 1 (6 1/2 oz.) can tuna, drained; 1/2 c. vegetable oil; 3 eggs; 1 tsp. dried oregano leaves; 1 tsp. salt; 1/2 tsp. pepper

Try this homemade Zucchini-Seafood Casserole recipe the whole family will love. Made with zucchini, Bisquick, shredded sharp American cheese and onion. …

This Zucchini-Seafood Casserole relies on simple, everyday ingredients such as bisquick, chopped onion, vegetable oil and eggs. It comes together quickly and makes 4 servings, at about 832 kcal each. The step-by-step instructions below are written to be easy to follow, even on a busy day.

It's versatile enough for an easy weeknight dinner yet satisfying enough for guests at the weekend. Serve it with your favorite sides, and keep any leftovers for a quick meal the next day.

Updated Jun 30, 2026

Serves 4 Seafood

Tips for the best results

Read through all the steps once before you start and measure out your ingredients first — it makes everything go more smoothly.
Taste as you go and adjust the seasoning before serving.
Avoid overcrowding the pan — cook in batches if needed for the best texture.
Let the dish rest for a few minutes before serving so the flavors settle.
Store leftovers in an airtight container in the fridge and enjoy within a few days.

Variations & substitutions

Feel free to swap in similar ingredients you already have on hand and adjust seasoning to taste.

No specific allergen information. Please check the ingredient list for possible allergens.

My Personal Notes

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Zucchini-Seafood Casserole

Tips for the best results

Variations & substitutions

My Personal Notes

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