How many servings does this recipe make?

This recipe makes 4 servings. You can adjust the portion size directly on this page.

What ingredients do I need for Ziti Spaghetti Casserole?

You need 12 ingredients. The key ingredients include: 1/2 lb. Italian sausage, 1 large onion, chopped, 1/2 tsp. Italian seasoning, 48 oz. can spaghetti sauce, and more.

Is Ziti Spaghetti Casserole suitable as pasta & noodles?

Yes, Ziti Spaghetti Casserole falls under the Pasta & Noodles category and is a great choice for this type of meal.

How do I store leftover Ziti Spaghetti Casserole?

Store leftovers in an airtight container in the refrigerator for up to 3–4 days. Reheat gently before serving.

Ziti Spaghetti Casserole Recipe

Name: Ziti Spaghetti Casserole
Prep time: 15 min
Cook time: 30 min
Total time: 45 min
Yield: 4 servings
Ingredients: 1/2 lb. Italian sausage; 1 large onion, chopped; 1/2 tsp. Italian seasoning; 48 oz. can spaghetti sauce; 1 c. water; 8 oz. ziti pasta; 12 oz. shredded Mozzarella; 1/2 c. shredded Parmesan; 1/2 lb. ground beef; 1/2 tsp. garlic; 1/2 tsp. salt; 3 1/2 oz. sliced pepperoni

Try this homemade Ziti Spaghetti Casserole recipe the whole family will love. Made with Italian sausage, onion, Italian seasoning and spaghetti sauce. E…

This Ziti Spaghetti Casserole relies on simple, everyday ingredients such as italian sausage, large onion, chopped, italian seasoning and can spaghetti sauce. It comes together quickly and makes 4 servings, at about 740 kcal each. The step-by-step instructions below are written to be easy to follow, even on a busy day.

It's versatile enough for an easy weeknight dinner yet satisfying enough for guests at the weekend. Serve it with your favorite sides, and keep any leftovers for a quick meal the next day.

Updated Jun 30, 2026

Serves 4 Pasta & Noodles

Tips for the best results

Read through all the steps once before you start and measure out your ingredients first — it makes everything go more smoothly.
Taste as you go and adjust the seasoning before serving.
Avoid overcrowding the pan — cook in batches if needed for the best texture.
Let the dish rest for a few minutes before serving so the flavors settle.
Store leftovers in an airtight container in the fridge and enjoy within a few days.

Variations & substitutions

Feel free to swap in similar ingredients you already have on hand and adjust seasoning to taste.

No specific allergen information. Please check the ingredient list for possible allergens.

My Personal Notes

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Ziti Spaghetti Casserole

Tips for the best results

Variations & substitutions

My Personal Notes

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