Try this homemade Sis' Chicken Broccoli Casserole recipe the whole family will love. Made with broccoli, chicken, cream of chicken soup and mayonnaise. …
This Sis' Chicken Broccoli Casserole relies on simple, everyday ingredients such as cream of chicken soup, mayonnaise (or less), lemon juice and sharp grated cheese. It comes together quickly and makes 4 servings, at about 972 kcal each. The step-by-step instructions below are written to be easy to follow, even on a busy day.
It's versatile enough for an easy weeknight dinner yet satisfying enough for guests at the weekend. Serve it with your favorite sides, and keep any leftovers for a quick meal the next day.
Updated Jun 30, 2026