Try this homemade Mary'S Hamburger Casserole recipe the whole family will love. Made with Tostitos, ground chuck, cream of chicken and cream of mushroom…
This Mary'S Hamburger Casserole relies on simple, everyday ingredients such as ground chuck, cream of chicken and cream of mushroom. It comes together quickly and makes 4 servings, at about 393 kcal each. The step-by-step instructions below are written to be easy to follow, even on a busy day.
It's versatile enough for an easy weeknight dinner yet satisfying enough for guests at the weekend. Serve it with your favorite sides, and keep any leftovers for a quick meal the next day.
Updated Jun 30, 2026