How many servings does this recipe make?

This recipe makes 4 servings. You can adjust the portion size directly on this page.

What ingredients do I need for Easy Italian Casserole?

You need 15 ingredients. The key ingredients include: 1 lb. ground beef, 1/2 c. chopped onion, 1 (16 oz.) can tomato sauce, 1 (4 oz.) can mushroom pieces, and more.

Is Easy Italian Casserole suitable as meat & poultry?

Yes, Easy Italian Casserole falls under the Meat & Poultry category and is a great choice for this type of meal.

How do I store leftover Easy Italian Casserole?

Store leftovers in an airtight container in the refrigerator for up to 3–4 days. Reheat gently before serving.

Easy Italian Casserole Recipe

Name: Easy Italian Casserole
Prep time: 15 min
Cook time: 30 min
Total time: 45 min
Yield: 4 servings
Ingredients: 1 lb. ground beef; 1/2 c. chopped onion; 1 (16 oz.) can tomato sauce; 1 (4 oz.) can mushroom pieces; 1 Tbsp. sugar; 1/2 tsp. dried oregano; 1/2 tsp. dried basil; 1/4 tsp. salt; 1/4 tsp. pepper; 1/2 tsp. garlic powder; 2 c. Bisquick; 1/2 c. milk; 1 egg; 8 slices American cheese; 1/4 c. Parmesan cheese

Try this homemade Easy Italian Casserole recipe the whole family will love. Made with ground beef, onion, tomato sauce and mushroom pieces. Easy step-by…

This Easy Italian Casserole relies on simple, everyday ingredients such as ground beef, chopped onion, (16 oz.) can tomato sauce and (4 oz.) can mushroom pieces. It comes together quickly and makes 4 servings, at about 687 kcal each. The step-by-step instructions below are written to be easy to follow, even on a busy day.

It's versatile enough for an easy weeknight dinner yet satisfying enough for guests at the weekend. Serve it with your favorite sides, and keep any leftovers for a quick meal the next day.

Updated Jun 30, 2026

Serves 4 Meat & Poultry

Tips for the best results

Read through all the steps once before you start and measure out your ingredients first — it makes everything go more smoothly.
Taste as you go and adjust the seasoning before serving.
Avoid overcrowding the pan — cook in batches if needed for the best texture.
Let the dish rest for a few minutes before serving so the flavors settle.
Store leftovers in an airtight container in the fridge and enjoy within a few days.

Variations & substitutions

Brown sugar instead of white sugar adds a deeper, more caramel-like flavor.

No specific allergen information. Please check the ingredient list for possible allergens.

My Personal Notes

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Easy Italian Casserole

Tips for the best results

Variations & substitutions

My Personal Notes

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