How many servings does this recipe make?

This recipe makes 4 servings. You can adjust the portion size directly on this page.

What ingredients do I need for Derek'S South Of The Border Casserole?

You need 10 ingredients. The key ingredients include: 1 1/2 lb. ground beef, 1 can green chilies, diced, 1 can Ro-Tel tomatoes, 1 can cream of mushroom soup, and more.

Is Derek'S South Of The Border Casserole suitable as soups & stews?

Yes, Derek'S South Of The Border Casserole falls under the Soups & Stews category and is a great choice for this type of meal.

How do I store leftover Derek'S South Of The Border Casserole?

Store leftovers in an airtight container in the refrigerator for up to 3–4 days. Reheat gently before serving.

Derek'S South Of The Border Casserole Recipe

Name: Derek'S South Of The Border Casserole
Prep time: 15 min
Cook time: 30 min
Total time: 45 min
Yield: 4 servings
Ingredients: 1 1/2 lb. ground beef; 1 can green chilies, diced; 1 can Ro-Tel tomatoes; 1 can cream of mushroom soup; 1/2 pt. sour cream; 1/2 medium onion, finely chopped; salt and pepper to taste; 1 Tbsp. chili powder; 1 bag Doritos nacho chips; 2 c. Cheddar cheese

Try this homemade Derek'S South Of The Border Casserole recipe the whole family will love. Made with ground beef, green chilies, Ro-Tel tomatoes and cre…

This Derek'S South Of The Border Casserole relies on simple, everyday ingredients such as ground beef, green chilies, diced, ro-tel tomatoes and cream of mushroom soup. It comes together quickly and makes 4 servings, at about 983 kcal each. The step-by-step instructions below are written to be easy to follow, even on a busy day.

It works as a light main on its own or as a starter alongside crusty bread, and it's just as good for a cozy night in as it is for feeding a crowd. Leftovers keep well, so it's a smart choice for meal prep too.

Updated Jun 30, 2026

Serves 4 Soups & Stews

Tips for the best results

Read through all the steps once before you start and measure out your ingredients first — it makes everything go more smoothly.
Taste as you go and adjust the seasoning before serving.
Avoid overcrowding the pan — cook in batches if needed for the best texture.
Let the dish rest for a few minutes before serving so the flavors settle.
Store leftovers in an airtight container in the fridge and enjoy within a few days.

Variations & substitutions

Coconut cream is a reliable plant-based alternative to dairy cream.

No specific allergen information. Please check the ingredient list for possible allergens.

My Personal Notes

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Derek'S South Of The Border Casserole

Tips for the best results

Variations & substitutions

My Personal Notes

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Frequently Asked Questions