Try this homemade Blackened Tilapia Po' Boy recipe the whole family will love. Made with tilapia, Cajun seasoning, Mayonnaise and baguette. Easy step-by…
This Blackened Tilapia Po' Boy relies on simple, everyday ingredients such as tilapia fillets (1-1/4 lb.), cajun seasoning, divided and shredded romaine lettuce. It comes together quickly and makes 4 servings, at about 153 kcal each. The step-by-step instructions below are written to be easy to follow, even on a busy day.
It's versatile enough for an easy weeknight dinner yet satisfying enough for guests at the weekend. Serve it with your favorite sides, and keep any leftovers for a quick meal the next day.
Updated Jun 30, 2026