How many servings does this recipe make?

This recipe makes 4 servings. You can adjust the portion size directly on this page.

What ingredients do I need for Ziti Pepperoni Casserole?

You need 10 ingredients. The key ingredients include: 1 (16 ounce) box ziti pasta, cooked and drained, 1 (32 ounce) jar spaghetti sauce, 1/2 lb mozzarella cheese, grated (or more), 1/2 lb cheddar cheese, grated (or more), and more.

Is Ziti Pepperoni Casserole suitable as pasta & noodles?

Yes, Ziti Pepperoni Casserole falls under the Pasta & Noodles category and is a great choice for this type of meal.

How do I store leftover Ziti Pepperoni Casserole?

Store leftovers in an airtight container in the refrigerator for up to 3–4 days. Reheat gently before serving.

Ziti Pepperoni Casserole Recipe

Name: Ziti Pepperoni Casserole
Prep time: 15 min
Cook time: 30 min
Total time: 45 min
Yield: 4 servings
Ingredients: 1 (16 ounce) box ziti pasta, cooked and drained; 1 (32 ounce) jar spaghetti sauce; 1/2 lb mozzarella cheese, grated (or more); 1/2 lb cheddar cheese, grated (or more); 1/2 lb pepperoni, chopped; 1 lb cottage cheese; optional additions; bell pepper; mushroom; onion

Try this homemade Ziti Pepperoni Casserole recipe the whole family will love. Made with pasta, spaghetti sauce, mozzarella cheese and cheddar cheese. Ea…

This Ziti Pepperoni Casserole relies on simple, everyday ingredients such as pepperoni, chopped, cottage cheese, optional additions and bell pepper. It comes together quickly and makes 4 servings, at about 953 kcal each. The step-by-step instructions below are written to be easy to follow, even on a busy day.

It's versatile enough for an easy weeknight dinner yet satisfying enough for guests at the weekend. Serve it with your favorite sides, and keep any leftovers for a quick meal the next day.

Updated Jun 30, 2026

Serves 4 Pasta & Noodles

Tips for the best results

Read through all the steps once before you start and measure out your ingredients first — it makes everything go more smoothly.
Taste as you go and adjust the seasoning before serving.
Avoid overcrowding the pan — cook in batches if needed for the best texture.
Let the dish rest for a few minutes before serving so the flavors settle.
Store leftovers in an airtight container in the fridge and enjoy within a few days.

Variations & substitutions

Feel free to swap in similar ingredients you already have on hand and adjust seasoning to taste.

No specific allergen information. Please check the ingredient list for possible allergens.

My Personal Notes

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Ziti Pepperoni Casserole

Tips for the best results

Variations & substitutions

My Personal Notes

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