Cheesy Ham-Penne Casserole Recipe

Name: Cheesy Ham-Penne Casserole
Prep time: 15 min
Cook time: 30 min
Total time: 45 min
Yield: 4 servings
Ingredients: 16 ounces penne pasta, cooked and drained (measure 16 ounces uncooked, I use half of a 900-gram package); 3 cups cubed cooked ham (or use as much as desired); 5 tablespoons butter; 1 teaspoon mustard powder; 1 teaspoon ground black pepper; 1 teaspoon seasoning salt (or 1/2 teaspoon white salt); 1/4 teaspoon cayenne pepper (optional or to taste); 1 small onion, finely chopped; 1 tablespoon fresh minced garlic (or to taste); 1/4 cup all-purpose flour; 3 cups half-and-half cream (or use half milk and cream); 2/3 cup grated parmesan cheese, divided; 4 1/2 cups grated cheddar cheese (a little more won't hurt)

Servings: persons

16 ounces penne pasta, cooked and drained (measure 16 ounces uncooked, I use half of a 900-gram package)
3 cups cubed cooked ham (or use as much as desired)
5 tablespoons butter
1 teaspoon mustard powder
1 teaspoon ground black pepper
1 teaspoon seasoning salt (or 1/2 teaspoon white salt)
1/4 teaspoon cayenne pepper (optional or to taste)
1 small onion, finely chopped
1 tablespoon fresh minced garlic (or to taste)
1/4 cup all-purpose flour
3 cups half-and-half cream (or use half milk and cream)
2/3 cup grated parmesan cheese, divided
4 1/2 cups grated cheddar cheese (a little more won't hurt)

1
Set oven to 350 degrees F.
2
Grease a 13 x 9-inch baking dish.
3
Place the cooked penne and the ham into a large bowl; set aside.
4
In a medium saucepan melt butter over medium heat.
5
Add in mustard powder, black pepper, seasoned salt and cayenne pepper and onion, stir and cook for about 4 minutes.
6
Add in garlic; cook stirring for 2 minutes.
7
Add in flour and mix continously for 2 minutes.
8
Slowly add in the cream and 1/3 cup Parmesan cheese; cook stirring over medium-low heat until bubbly.
9
Reduce heat to low and stir in the cheddar cheese until completely melted.
10
Pour the sauce over the cooked pasta and ham; toss until well combined.
11
Transfer to a greased baking dish.
12
Sprinkle the top with about 1/3 cup or more Parmesan cheese.
13
Cover and bake in a 350 degree F oven for about 45 minutes or until hot and bubbly.

2078

kcal

Calories

146

Fat

103

Carbs

Protein

Fat Carbs Protein

* Per serving · 4 servings · Values may vary.

Tips for the best results

Read through all the steps once before you start and measure out your ingredients first — it makes everything go more smoothly.
Taste as you go and adjust the seasoning before serving.
Avoid overcrowding the pan — cook in batches if needed for the best texture.
Let the dish rest for a few minutes before serving so the flavors settle.
Store leftovers in an airtight container in the fridge and enjoy within a few days.

Variations & substitutions

Use a neutral oil or a plant-based spread in place of butter for a dairy-free version.
A good 1:1 gluten-free flour blend works well if you need a gluten-free version.
Coconut cream is a reliable plant-based alternative to dairy cream.

No specific allergen information. Please check the ingredient list for possible allergens.

My Personal Notes

Saved locally in your browser — visible only to you.

How did you like this recipe?

This recipe makes 4 servings. You can adjust the portion size directly on this page.

You need 13 ingredients. The key ingredients include: 16 ounces penne pasta, cooked and drained (measure 16 ounces uncooked, I use half of a 900-gram package), 3 cups cubed cooked ham (or use as much as desired), 5 tablespoons butter, 1 teaspoon mustard powder, and more.

Yes, Cheesy Ham-Penne Casserole falls under the Pasta & Noodles category and is a great choice for this type of meal.

Store leftovers in an airtight container in the refrigerator for up to 3–4 days. Reheat gently before serving.

That's it — enjoy your meal!

Cheesy Ham-Penne Casserole

Tips for the best results

Variations & substitutions

My Personal Notes

How did you like this recipe?

Frequently Asked Questions