Bake this irresistible Brenda's John Wayne Casserole at home. Made with ground beef, taco, sour cream and cheddar cheese. Easy step-by-step instructions…
This Brenda's John Wayne Casserole relies on simple, everyday ingredients such as taco seasoning (1.25-ounce), sour cream, shredded cheddar cheese and biscuit mix. It comes together quickly and makes 4 servings, at about 969 kcal each. The step-by-step instructions below are written to be easy to follow, even on a busy day.
Whether you're rounding off a family dinner, bringing a treat to a gathering, or simply satisfying a sweet craving, this Brenda's John Wayne Casserole delivers. Serve it warm or at room temperature, and add a scoop of ice cream or a spoonful of whipped cream for an extra-special finish.
Updated Jun 30, 2026